Carro. One thing I think is certain, that if every practitioner will preferve a portion of infection in each cafe under his care, and, efpecially, if he fecures the genuine, (primary) fcab, we never shall lofe this invaluable bleffing.It is time alfo for people to reflect, that this disease is equally mild at all seasons of the year, and, that as the small-pox is almost uniformly in our city, it is of great confequence to fecure their infants from its attack, without waiting for those periods to which they have been accustomed in the small-pox.---I lately vaccinated in the Pennsylvania Hofpital an infant only three days old, who went through the difeafe in the moft eafy manner,--and on the twelfth day, I tefted her with fmall-pock virus without effect,---fo that by the time the mother was able to leave the lying-in-ward, her child was also secured against the ravages of this enemy to mankind. E.

At the Vaccine-Pock Inftitution, Golden Square, in the month of June of the present year, a number of subjects who had undergone vaccination in the year 1800, were fubmitted to the variolous teft, under circumstances the most favourable for exciting the fmall-pox.---Some alfo who had been vaccinated by Dr. Pearfon early in 1799, have likewise been tested, but with the refult that might be expected in favour of vaccination.

Tilloch.

It appears that vaccination is now fully established throughout all the British prefidencies in India.

Dr. Jenner has received from Dr. Sacco, of Milan, pofitive proof of the validity of his opinion, that the vaccine owes its origin to the greafe of the horfe.* A coach-horfe of Dr. S. having the greafe, communicated feveral puftules to the hands. of the coachman who attended to the fore, having all the cha

This proof is of the strongest kind, as Dr. Sacco not only doubted Dr. Jenner's opinion on this point, but imagined he poffeffed facts to overthrow it completely.

racteristic marks of those derived from the cow:---another coachman foon after was affected in a fimilar way;---from whofe puftules Dr. S. inoculated nine children and a cow. Three of the children were infected, having the disease exactly as if it had been communicated from the cow.---The matter - from these children was fuccefsful in others ;---and at the time the account was tranfmitted, it had reproduced itself correctly a fourth time. Dr. S. has inoculated fix other children with the matter of greafe, on two of whom it fucceeded with all the genuine characters of the vaccine.---A plate of the difeafe in the foot of the horse is intended to be given by Dr. Sacco. Med. Phyf. Jour.

By a very extraordinary coincidence, the prophylactic power of the vaccine, was discovered in South America, about the fame period, in which it was promulgated in England by Dr. Jenner, according to information I received from the learned and interefting Baron Humboldt whilft he remained in Philadelphia.---It was not, however, communicated by inoculation from one perfon to another.

E.

Mr. Schrader, apothecary at Berlin, has made the interesting. difcovery, that the Pruffic acid is contained in the aqua lauroterafi, and the diftilled water from the flowers of the peach tree, as likewife in the infufion of bitter almonds.---He was led to this discovery by obferving, that the Pruffic acid has the quality common with thofe diftilled waters and infufions, of killing animals; and, that the Pruffic acid, as well as the abovementioned water, poffeffes the smell of bitter almonds.

This discovery is likely to be very advantageous to medicinè as well as to the arts; and the author thinks it probable, that what is hitherto called the narcotic principle may be nothing but the Pruffic acid: and, in order to prove this conjecture, he intends making experiments with opium, hyofciamus, belJadonna, and the other narcotics.

Med.& Phyf. Journal,

Dr. Schaub has difcovered a new method of obtaining Prufsic acid in a state of abfolute purity. The process consists in pouring upon one part of Pruffian blue, half as much fulphuric acid, diluted with an equal quantity of water, and fubfequent diftillation. The Pruffic acid paffes over in alkohol; its odour greatly resembles the water of the lauro-cerafus. It is a deadly poifon to animals. Ibid.

The new metal which has been announced to the public under the name of Palladium, is found to be a composition of two parts of platina and one of mercury.

Ibid.

Mr. Hunter of Dumbarton, in order to encourage the more general ufe of a valuable remedy, gives an account of a lump of acetite of lead, weighing not less than a pound, which was accidentally cut up, by an old fhort-fighted woman, with cabbage, for dinner, and which was entirely eaten by the master, mistress, a daughter, her husband, and two apprentices.---Aa emetic was given to five of them which operated well; but the fixth, one of the apprentices, as he felt nothing uneafy about him refused to take any thing;--yet he never had the smallest complaint, and was as regular in his bowels as before.

Ibid.

Dr. Richardfon of Rippon, in the Philofophical Transactions, volume 11th. article 22. has given a curious and accurate detail of the aphis, puceron, or vine-fretter, in which he speaks of the friends and enemies of that race, which ejects from the rectum, the fubftance called honey dew. Among the friends of the aphis Dr. R. reckons the ant and the bee. The ant is a conftant visitor, the bee only when flowers are fcarce. The ant, he adds, will fuck in the delicious nectar, while the aphides are in the act of discharging it from the anus, but the bees only collect it from the leaves on which it has fallen.

Whilft obferving this curious infect on the vine, I noticed the ants running about them with confiderable diligence; at times fuddenly stopping, and as quickly renewing their progress: up

on examining them with a magnifier, I observed the ant when he stopped, apply his fore-legs or his antennæ with great velocity over the aphis, who almoft immediately elevated his rump, and propelled a minute drop of this honey dew; this was inftantly feized upon and fwallowed by the ant, who immediately quitted his station to hunt out another, fit for emitting his food. It appeared altogether a degree of inftinct in the ant, by which he discovered, which, of a great number of aphides was prepared to emit it; for he continued running amongst them, till one was found fit for his purpose, when the fame tickling was renewed, till the emiffion took place: by these means the lank body of the ant foon plumped up, and others fucceeded to him, to renew their depredations on the aphis, who did not feem disturbed by the process.

E.

Dr. Ackermann, of Mentz, has made feveral galvanic experiments on the body of a beheaded perfon a quarter of an hour after decapitation. The battery which he used confifted of one hundred ftrata of zinc and copper plates. A small sponge, moftened with a folution of ammonia, and connected with the hydrogen pole, being introduced into the inteftinum rectum, another punge was laid on the wound of the neck, and the head placed above it, into the right ear of which a small sponge had been put, tied to a wire, whofe end was held in the hand. On touching the oxygen pole of the battery, all the muscles of the body were thrown into violent convulfions, the fpine lifting itfelf and bending repeatedly; both arms forcing themselves out of the hands of the affiftant were forcibly drawn towards the body: the muscles of the face were likewife convulfed, and the mafticatories opened and clofed the jaws with gnashing of the teeth. In the experiments which were made on the body alone, the muscles of the extremities were much convulfed, and in those made on the head only, the eye-balls were violently rolled within their cavities. All thefe contractions continued above an hour; and even when the body had received the temperature of the atmosphere, flight contractions could be perceived. Med. Phyf. Journal.

Dr. Desfontaines of St. Germain, read at the medical fociety of Paris, an account of an extraordinary disease followed by death, occafioned by an infect found living in the substance of the liver upon diffection, "towards the middle of the concave furface of the great lobe was perceived a kind of cavity fix or feven lines in diameter, and four or five in depth, filled with a black thick humour, and out of which came an infect yet alive; it was a worm of an extraordinary kind, and refembling no way those which practitioners have defcribed as hepatic worms. It was four inches long, and of the thickness of a silk worm of the largest fize; its colour was of a brownish red, and its body was articulated in the form of rings; each was marked by a white fpot, in the middle of which was implanted a hair of a resisting nature, and extremely fharp, and which, feen through a lens, resembled the quills of a porcupine; the head of the infect was armed with a kind of proboscis also articulated; the inferior extremity was terminated by a large flat tail, fimilar to that of a crab." Ibid.

Dr. Deiman, of Amfterdam, employed the fur-oxygenated muriatic acid mixed with oil as one of the best external remedies in fcabies and other cutaneous diseases, and he fucceeded in curing a very obftinate fpecies of scabies with a liniment, in which fixty drops of the acid were added to one ounce of oil. He used it with equal fuccefs in tinea capitis, and herpetic complaints of the most obftinate kind. Dr. Binkman of the fame place, praises like wife this combination, but in tinea capitis he advises to add more acid. The oil is mixed with the acid, by shaking it in a glass vessel, which is well clofed. No more than one ounce ought to be prepared at once. The vessel, in which the liniment is preserved, must be put in a dark place, and be fhaken before it is applied.

Ibid.

Mr. Ring ftrongly recommends the following preparation of burnt sponge in the cure of bronchocele.